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Course: ORE Part 1
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ORE Part 1

Full ORE Part 1 Lessons

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9.1 Histology

Tooth Histology

  • Peritubular dentine is the most mineralized part of dentine, providing significant structural strength. [Q0009]
  • Dentinal tubules make up 0.5% of the total dentine surface at a distance of 0.5mm from the pulp, reflecting their density near the pulp. [Q0013]
  • The junction between primary and secondary dentine is marked by a resting line, indicating a pause in dentine formation. [Q0014]
  • Keratocysts typically have a more aggressive expansion pattern compared to ameloblastomas. [Q3084]
  • Yes, ameloblastomas appear as islands of cells with a prominent outer layer of basal cells. [Q3225]
  • Yes, ameloblastomas are more common in middle-aged individuals. [Q3226]
  • No, ameloblastomas are typically benign but can be locally aggressive. [Q3229]
  • Yes, ameloblastomas can appear as islands of epithelium separated by pink collagenous bands. [Q3230]
  • Yes, apoptosis can be gene-activated, physiological, or pathological. [Q3291]
  • Autophagy is the process responsible for removing damaged organelles and atrophic cells. [Q3325]
  • Bone is comprised of compact and spongy bone. [Q3376]
  • Osteoblasts and osteoclasts are responsible for bone deposition and resorption, respectively. [Q3377]
  • Yes, caseous necrosis is distinctive to foci of tuberculous infections. [Q3419]
  • Cellular swelling is often the first manifestation of cell injury. [Q3431]
  • Dentigerous cysts can often be mistaken for ameloblastoma due to their similar location. [Q3577]
  • Dentigerous cysts are typically located at the angle of the mandible. [Q3578]
  • Dentigerous cysts are usually unilocular radiolucent lesions. [Q3579]
  • White sponge nevus presents as bilateral thick white patches. [Q3596]
  • Enamel lamellae do not extend the entire thickness of the enamel. [Q3668]
  • Enamel pearls are occasionally found in the cervical margins and bifurcation areas. [Q3670]
  • Enamel spindles do not extend to the surface of the enamel. [Q3671]
  • Enamel tufts extend from the enamel-dentine junction into the inner third of the enamel. [Q3672]
  • Enamel tufts occur at 100 micron intervals. [Q3673]
  • Eukaryotic cells are typically greater than 5 microns. [Q3692]
  • Eukaryotic cells have complex structures like the endoplasmic reticulum and Golgi apparatus. [Q3693]
  • Exfoliative cytology can be used to diagnose certain types of cancer. [Q3697]
  • Exfoliative cytology is reliable when used in conjunction with other diagnostic tests. [Q3698]
  • Cellular atypia and mitotic figures are features of epithelial dysplasia. [Q3716]
  • Haematoxylin stains tissues blue, while eosin stains them red. [Q3858]
  • Immunostaining relies on antibody-antigen binding to target specific molecules. [Q4037]
  • A 10-gauge needle is not typically used in fine needle aspiration biopsy. [Q4078]
  • Fresh tissues in frozen sections are typically frozen at much lower temperatures, around -20°C to -30°C. [Q4079]
  • Increased cytosolic calcium can lead to cellular death by activating various cell death pathways. [Q4147]
  • No, inflammation is typically a reaction to necrosis, not apoptosis. [Q4157]
  • Yes, keratocysts can cause resorption or displacement of adjacent teeth, but it is rare. [Q4214]
  • Liquefactive necrosis can be triggered by both bacterial and fungal infections. [Q4256]
  • Liquid nitrogen is used to freeze tissue for frozen section analysis. [Q4257]
  • Immunostaining methods can detect lymphomas, pemphigus, and pemphigoid. [Q4285]
  • Megamitochondria are commonly observed in liver cells. [Q4325]
  • Sclerotic dentine is caused by chronic tooth wear. [Q4343]
  • Hutchinson’s incisors and mulberry molars are dental defects caused by congenital syphilis. [Q4358]
  • Necrosis can cause both enzyme digestion of the cell and denaturation of proteins. [Q4413]
  • Necrosis can be caused by both loss of blood supply and toxins leading to cellular changes. [Q4414]
  • Many malignant neoplasms have genetic abnormalities. [Q4814]
  • Squamous cell carcinoma is diagnosed through histopathological examination of a biopsy. [Q4827]
  • The basal cells in Ameloblastoma exhibit reversed polarity. [Q4921]
  • Biopsy specimens are commonly preserved in 10% formal saline for histological examination. [Q4928]
  • Type I collagen is found in dentinal tubules and provides structural support. [Q6069]

Gingival and Periodontal Histology

  • Acellular cementum covers the root adjacent to the dentine. [Q3152]
  • Granulomatous inflammation is characterized by the presence of macrophages. [Q3427]
  • Cellular cementum is typically found in the apical area overlying the acellular cementum. [Q3428]
  • Yes, chronic desquamative gingivitis can be associated with skin lichen planus. [Q3460]
  • Acantholysis describes the separation of epithelium from the connective tissue. [Q3516]
  • Delayed healing for weeks often indicates an infection. [Q3554]
  • Epulis is a characteristic of gingival hyperplasia. [Q3684]
  • Fibrous epulis is a nodule of granulation tissue. [Q3722]
  • Mineralizing epulis is another name for peripheral ossifying fibroma. [Q4345]
  • Cementum can be either cellular or acellular, depending on its location and function. [Q4949]

Salivary Gland Histology

  • Decreased acinar cells are a characteristic finding in acinar atrophy. [Q3044]
  • Fordyce spots are typically found on the labial and buccal mucosa. [Q3763]
  • Fordyce spots are cream-colored, occasionally prominent, and very numerous. [Q3764]
  • Fordyce’s spots are ectopic sebaceous glands, not minor salivary glands. [Q3765]

Neural and Vascular Histology

  • Carotid body tumors can cause either unilateral or bilateral swelling at the carotid bifurcation. [Q3415]
  • A thyroglossal duct cyst is located in the middle of the neck just above the thyroid gland. [Q3545]
  • Myocardial necrosis is typically coagulative due to ischemia. [Q4404]
  • Prions primarily affect neural tissue. [Q4670]